Cancer
in the liver has traditionally been approached with surgical
resection or chemotherapy given intravenously. Recently techniques
for the local ablation of liver tumors have become popular.
These techniques may avoid an open operation and may, in some
cases, be safer than surgical removal of the tumors. Local ablation
has been studied in many forms including microwave, laser, high
intensity focused ultrasound, local injection of alcohol or
chemotherapy, and cryotherapy. The thermal ablation of tumors
involves heating the tumors to extremely high temperatures until
the tumor cells die. This heating can be performed simply and
reliably using radiofreqency waves in a technique called radiofrequency
ablation (RFA). This technique has already been extensively
studied and has shown to be a safe and reliable means of ablating
liver tumors. This procedure can be performed as an open operation
or at the time of laparoscopy. The tumor is identified using
an ultrasound probe placed on the liver. The needle tip radiofrequency
probe is then inserted into the tumor and the heating is begun.
Care must be taken to make sure that all margins of the spherical
tumor are heated to an appropriate temperature to allow for
a complete ablation of the tumor. This requires moderate experience
to be successful with this technique. The radiofrequency approach
has the added benefit of preventing bleeding as the heat cauterizes
blood vessels and destroys them.
While this technique is exciting and
potentially much easier on the patient, it must be considered
only one tool in the armamentarium of treatment for liver tumors.
In some cases, a combination of surgical removal and radiofrequency
ablation may be the best approach. These decisions are made
after carefully examining the extent and location of tumors
within the liver.