Virus Classification

Virus classificationssRNA (Group IV) viruses with vertebrate hosts,
Virus classification involves naming and placing virusesPicornavirales contains small (+) strand ssRNA viruses
into a taxonomic system. Like the relatively consistentthat infect a variety of plant, insect, and animal hosts,
classification systems seen for cellular organisms, virusand Tymovirales contains monopartite ssRNA viruses
classification is the subject of ongoing debate andthat infect plants. Other variations occur between the
proposals. This is largely due to the pseudo-livingorders, for example, Nidovirales are isolated for their
nature of viruses, which are not yet definitively living ordifferentiation in expressing structural and non-structural
non-living. As such, they do not fit neatly into theproteins separately. However, this system of
established biological classification system in place fornomenclature differs from other taxonomic codes on
cellular organisms, such as eukaryotes andseveral points. A minor point is that names of orders
prokaryotes.and families are italicized, as in the ICBN.[1] Most
Virus classification is based mainly on phenotypicnotably, species names generally take the form of
characteristics, including morphology, nucleic acid type,[Disease] virus. The establishment of an order is based
mode of replication, host organisms, and the type ofon the inference that the virus families contained within
disease they cause. A combination of two maina single order have most likely evolved from a
schemes is currently in widespread use for thecommon ancestor. The majority of virus families
classification of viruses. David Baltimore, a Nobelremain unplaced. Currently (2009) 6 orders, 87 families,
Prize-winning biologist, devised the Baltimore19 subfamilies, 348 genera, and 2,288 species of virus
classification system, which places viruses into one ofhave been defined[2].
seven groups. These groups are designated byBaltimore classification
Roman numerals and separate viruses based on theirThe Baltimore Classification of viruses is based on the
mode of replication, and genome type. Accompanyingmethod of viral mRNA synthesisBaltimore classification
this broad method of classification are specific naming(first defined in 1971) is a classification system that
conventions and further classification guidelines set outplaces viruses into one of seven groups depending on
by the International Committee on Taxonomy ofa combination of their nucleic acid (DNA or RNA),
Viruses.strandedness (single-stranded or double-stranded),
ICTV classificationSense, and method of replication. Other classifications
The International Committee on Taxonomy of Virusesare determined by the disease caused by the virus or
began to devise and implement rules for the namingits morphology, neither of which are satisfactory due
and classification of viruses early in the 1990s, anto different viruses either causing the same disease or
effort that continues to the present day. The ICTV islooking very similar. In addition, viral structures are often
the only body charged by the International Union ofdifficult to determine under the microscope. Classifying
Microbiological Societies (IUMS) with the task ofviruses according to their genome means that those in
developing, refining, and maintaining a universal virusa given category will all behave in a similar fashion,
taxonomy. The system shares many features with theoffering some indication of how to proceed with
classification system of cellular organisms, such asfurther research. Viruses can be placed in one of the
taxon structure. Viral classification starts at the level ofseven following groups:[3]
order and follows as thus, with the taxon suffixes• I: dsDNA viruses (e.g. Adenoviruses,
given in italics:Herpesviruses, Poxviruses)
Order (-virales)• II: ssDNA viruses (+)sense DNA (e.g.
Family (-viridae)Parvoviruses)
Subfamily (-virinae)• III: dsRNA viruses (e.g. Reoviruses)
Genus (-virus)• IV: (+)ssRNA viruses (+)sense RNA (e.g.
SpeciesPicornaviruses, Togaviruses)
So far, six orders have been established by the ICTV:• V: (−)ssRNA viruses (−)sense RNA (e.g.
the Caudovirales, Herpesvirales, Mononegavirales,Orthomyxoviruses, Rhabdoviruses)
Nidovirales, Picornavirales, and Tymovirales. These• VI: ssRNA-RT viruses (+)sense RNA with DNA
orders span viruses with varying host ranges.intermediate in life-cycle (e.g. Retroviruses)
Caudovirales are tailed dsDNA (group I)• VII: dsDNA-RT viruses (e.g. Hepadnaviruses)
bacteriophages, Herpesvirales contains largeHolmes classification
eukaryotic dsDNA viruses, Mononegavirales includesHolmes (1948) used Carolus Linnaeus's system of
non-segmented (-) strand ssRNA (Group V) plant andbinomial nomenclature to classify viruses into 3 groups
animal viruses, Nidovirales is composed of (+) strandunder one order, Virales.